iaafr
May 3, 2019, 1:02am
282
basically what im implying is if you posted surveys on social media about essential oils youd probably get a big sample of people who think they mostly helped too
insom
May 3, 2019, 1:02am
283
yeah those adverse effects were mostly dry mouth. I don't think that's a huge deal.
yns
May 3, 2019, 1:03am
285
when will he stop posting
insom
May 3, 2019, 1:03am
286
right, but there are not a lot of doctors who prescribe essential oils, if any. but there are loads of doctors who swear by it now. do you think that means nothing?
yns
May 3, 2019, 1:03am
287
I don’t think many doctors are prescribing and swearing by CBD oil dude
iaafr
May 3, 2019, 1:03am
288
yea doctors are fuckin stupid and getting a medical degree doesnt take that much critical thinking
1 Like
insom
May 3, 2019, 1:04am
289
well lets revisit this in 5 years and we'll see who was right
yns
May 3, 2019, 1:06am
290
How can you be this stupid?
iaafr
May 3, 2019, 1:09am
291
the last doctor i visited who i mentioned cbd to (i was trying to use some to help with a thrown out back) pretty much knew nothing about it
despite us being in california where i suspect cbd use is way higher than in most states
also the cbd didnt help nearly as much as lots of ibuprofen in that case
insom
May 3, 2019, 1:10am
293
Yeah, America is really far behind when it comes to using CBD, which is why saying the FDA hasn't approved it is such an outrageous thing to say
yns
May 3, 2019, 1:12am
294
This is like arguing about horoscopes with someone
insom
May 3, 2019, 1:14am
295
When you can't actually find anything bad to say about CBD so you just talk about Essential Oils and Horoscopes instead
iaafr
May 3, 2019, 1:14am
296
eh im finding some studies with like preliminary good results
M Iskedjian, B Bereza, A Gordon, C Piwko and TR Einarson,
Current medical research and opinion , Jan 2007
Debilitating pain, occurring in 50-70% of multiple sclerosis (MS) patients, is poorly understood and infrequently studied. We summarized efficacy and safety data of cannabinoid-based drugs for neuropathic pain.Studies were identified from Medline, Embase, and Cochrane databases; Bayer Healthcare provided additional trials.Accepted were randomized, double-blinded placebo-controlled trials of cannabinoid-based treatments for MS-related/neuropathic pain in adults > or = 18 years of age.Two reviewers identified studies and extracted data; a third adjudicated disagreements. Data included baseline and endpoint pain scores on visual analog or 11-point ordinal scales.Of 18 articles and three randomized controlled trial (RCT) reports identified, 12 articles and two reports were rejected (9 = inappropriate disease or outcome, 1 = duplicate, 1 = review, and 1 = abstract); six accepted articles and one RCT-report involved 298 patients (222 treated, 76 placebo); four examined Sativex (a cannabidiol/delta-9-tetrahydrocannabinol (THC) buccal spray) (observations = 196), five cannabidiol (n = 41), and three dronabinol (n = 91). Homogeneity chi(2) values were non-significant, allowing data combination. Analyses focused on baseline-endpoint score differences. The cannabidiol/THC buccal spray decreased pain 1.7 +/- 0.7 points (p = 0.018), cannabidiol 1.5 +/- 0.7 (p = 0.044), dronabinol 1.5 +/- 0.6 (p = 0.013), and all cannabinoids pooled together 1.6 +/- 0.4 (p < 0.001). Placebo baseline-endpoint scores did not differ (0.8 +/- 0.4 points, p = 0.023). At endpoint, cannabinoids were superior to placebo by 0.8 +/- 0.3 points (p = 0.029). Dizziness was the most commonly observed adverse event in the cannabidiol/THC buccal spray arms (39 +/- 16%), across all cannabinoid treatments (32.5 +/- 16%) as well as in the placebo arms (10 +/- 4%).Cannabinoids including the cannabidiol/THC buccal spray are effective in treating neuropathic pain in MS.This review was based on a small number of trials and patients. Pain related to MS was assumed to be similar to neuropathic pain.
SJ Ward, SD McAllister, R Kawamura, R Murase, H Neelakantan and EA Walker,
British journal of pharmacology , Feb 2014
Paclitaxel (PAC) is associated with chemotherapy-induced neuropathic pain (CIPN) that can lead to the cessation of treatment in cancer patients even in the absence of alternate therapies. We previously reported that chronic administration of the non-psychoactive cannabinoid cannabidiol (CBD) prevents PAC-induced mechanical and thermal sensitivity in mice. Hence, we sought to determine receptor mechanisms by which CBD inhibits CIPN and whether CBD negatively effects nervous system function or chemotherapy efficacy.The ability of acute CBD pretreatment to prevent PAC-induced mechanical sensitivity was assessed, as was the effect of CBD on place conditioning and on an operant-conditioned learning and memory task. The potential interaction of CBD and PAC on breast cancer cell viability was determined using the MTT assay.PAC-induced mechanical sensitivity was prevented by administration of CBD (2.5 - 10 mg·kg⁻¹) in female C57Bl/6 mice. This effect was reversed by co-administration of the 5-HT(1A) antagonist WAY 100635, but not the CB₁ antagonist SR141716 or the CB₂ antagonist SR144528. CBD produced no conditioned rewarding effects and did not affect conditioned learning and memory. Also, CBD + PAC combinations produce additive to synergistic inhibition of breast cancer cell viability.Our data suggest that CBD is protective against PAC-induced neurotoxicity mediated in part by the 5-HT(1A) receptor system. Furthermore, CBD treatment was devoid of conditioned rewarding effects or cognitive impairment and did not attenuate PAC-induced inhibition of breast cancer cell viability. Hence, adjunct treatment with CBD during PAC chemotherapy may be safe and effective in the prevention or attenuation of CIPN.
i am still highly skeptical about undiscovered drawbacks esp with long term use but my opinion is that i wouldnt be surprised if it ended up seeming like a decent option in some cases, esp for alleviating side effects of chemo or really severe conditions like MS
iaafr
May 3, 2019, 1:16am
297
my general impression is that cbd + thc is actually way more effective than just cbd for pain treatment specifically but therere still a ton of issues with thc use in general
iaafr
May 3, 2019, 1:20am
299
anyway in my spiritual worldview where cancer is just a manifestation of not living up to your dreams on the physical plane to punish you and give you one last chance at living the life you wanna live and marijuana use is a copout that lets you choose comfortable mediocrity, it makes total sense that marijuana fits really well as a way to alleviate side effects of chemo
yns
May 3, 2019, 1:30am
300
No I’m just calling you stupid for making claims you can’t prove yet
